course details
Endotoxin and mycoplasma analysis
June 24-25, 2027
Avans UAS
LUMC
Hogeschool Utrecht
Mycoplasma contamination in cell culture during the manufacturing process poses a potential health risk to patients. Therefore, regulatory bodies require manufacturers to test their biopharmaceutical products and ensure the absence of mycoplasmas in released products. This course provides an introduction to the field of mycoplasma testing. In addition, endotoxin testing is essential in cell and gene therapy to detect the presence of bacterial lipopolysaccharides, as even low levels can induce severe inflammatory reactions and/or sepsis and thereby compromise the safety and efficacy of the therapeutic product. This course provides an overview to endotoxin testing
Language
English
Entry level
Basic
Accreditation
Certificate of participation
Price
75 euros
Please check the provider’s website for registration and the current price
June 24-25, 2027
Avans UAS, Breda NL
2 days live course and 40 h self study
Notify me when available
Target audience
Life-science professionals with a BSc, MSc, or academic background, including ATMP operators, laboratory technicians, laboratory specialists, biotech/pharma employees, clinicians and healthcare analysts
Education level
Bachelor's/HBO level (EQF 6); Master's level (EQF 7); Doctoral/PhD level (EQF 8); Postgraduate education; Professional/continuing education
Learning outcomes
Understanding what exactly mycoplasma is
Knowledge of Mycoplasma detection systems
Evaluation of different Mycoplasma Kits (including real-time PCR based kits)
Understanding of endotoxins and their relevance
Knowledge of the history of endotoxin testing (LAL assay)
Knowledge of the different methodologies for endotoxin testing (Gel and kinetic methods) in e.g. ATMP laboratories
Knowledge about what the regulations are about Endotoxin Testing
Experience with endotoxin calculation
Topics
Cell biology
Cell culture & differentiation
Cell therapy
Cleanroom & aseptic processing
Clinical development
Contamination control
Genome editing
GMP
Laboratory techniques
Manufacturing & bioprocessing
Molecular biology
Professional & transferable skills
Quality assurance (QA)
Quality control (QC)
Learning experience
In-person
Lecture
Workshop
Hands-on laboratory
Demonstration
Case-based learning
Team/group work
Workshop
Hands-on laboratory
Demonstration
Case-based learning
Team/group work
Online
e-learning
Schedule
In-person
Weekdays
Online
Outside working hours
Flexible/self-paced
Variable schedule
Flexible/self-paced
Variable schedule
Price
75 euros
Please check the provider’s website for registration and the current price
June 24-25, 2027
Avans UAS, Breda NL
2 days live course and 40 h self study
Notify me when available 
